Therapeutic Application of Phage Capsule Depolymerases against K1, K5, and K30 Capsulated E. coli in Mice

Capsule depolymerase enzymes offer a promising class of new antibiotics. In vivo studies are encouraging but it is unclear how well this type of phage product will generalize in therapeutics, or whether different depolymerases against the same capsule function similarly. Here, in vivo efficacy was t...

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Detalles Bibliográficos
Autores principales: Lin, Han, Paff, Matthew L., Molineux, Ian J., Bull, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696595/
https://www.ncbi.nlm.nih.gov/pubmed/29201019
http://dx.doi.org/10.3389/fmicb.2017.02257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696595/
https://www.ncbi.nlm.nih.gov/pubmed/29201019
http://dx.doi.org/10.3389/fmicb.2017.02257

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