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Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease

Aerobic exercise is a promising behavioral therapy for Alzheimer's disease (AD), yet few studies have investigated the effect of aerobic exercise on cognition in AD. The purpose of this pilot study was to examine the effect of 6-month aerobic exercise on the change in executive function, global...

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Detalles Bibliográficos
Autores principales: Yu, Fang, Nelson, Nathaniel W., Savik, Kay, Wyman, Jean F., Dysken, Maurice, Bronas, Ulf G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696626/
https://www.ncbi.nlm.nih.gov/pubmed/21911546
http://dx.doi.org/10.1177/0193945911420174
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author Yu, Fang
Nelson, Nathaniel W.
Savik, Kay
Wyman, Jean F.
Dysken, Maurice
Bronas, Ulf G.
author_facet Yu, Fang
Nelson, Nathaniel W.
Savik, Kay
Wyman, Jean F.
Dysken, Maurice
Bronas, Ulf G.
author_sort Yu, Fang
collection PubMed
description Aerobic exercise is a promising behavioral therapy for Alzheimer's disease (AD), yet few studies have investigated the effect of aerobic exercise on cognition in AD. The purpose of this pilot study was to examine the effect of 6-month aerobic exercise on the change in executive function, global cognition, quality of life (QOL), and depression in community-dwelling older adults with mild to moderate AD. A single group, repeated measures design with outcomes measured at baseline, 3 months, and 6 months was used. Results show that there were no significant changes in any measures except for depression (p = .026). There was a trend toward improvement in executive function and QOL with moderate effect sizes (ESs) and a trend toward deterioration in global cognition with moderate to large ESs. Randomized controlled trials are needed to evaluate the therapeutic effect of aerobic exercise in older adults with AD.
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spelling pubmed-56966262017-11-21 Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease Yu, Fang Nelson, Nathaniel W. Savik, Kay Wyman, Jean F. Dysken, Maurice Bronas, Ulf G. West J Nurs Res Article Aerobic exercise is a promising behavioral therapy for Alzheimer's disease (AD), yet few studies have investigated the effect of aerobic exercise on cognition in AD. The purpose of this pilot study was to examine the effect of 6-month aerobic exercise on the change in executive function, global cognition, quality of life (QOL), and depression in community-dwelling older adults with mild to moderate AD. A single group, repeated measures design with outcomes measured at baseline, 3 months, and 6 months was used. Results show that there were no significant changes in any measures except for depression (p = .026). There was a trend toward improvement in executive function and QOL with moderate effect sizes (ESs) and a trend toward deterioration in global cognition with moderate to large ESs. Randomized controlled trials are needed to evaluate the therapeutic effect of aerobic exercise in older adults with AD. 2011-09-12 2013-01 /pmc/articles/PMC5696626/ /pubmed/21911546 http://dx.doi.org/10.1177/0193945911420174 Text en http://creativecommons.org/licenses/by/2.0/ Reprints and permission: sagepub.com/journalsPermissions.nav
spellingShingle Article
Yu, Fang
Nelson, Nathaniel W.
Savik, Kay
Wyman, Jean F.
Dysken, Maurice
Bronas, Ulf G.
Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease
title Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease
title_full Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease
title_fullStr Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease
title_full_unstemmed Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease
title_short Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer's Disease
title_sort affecting cognition and quality of life via aerobic exercise in alzheimer's disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696626/
https://www.ncbi.nlm.nih.gov/pubmed/21911546
http://dx.doi.org/10.1177/0193945911420174
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