Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms

Little is known about how aerobic exercise affects Alzheimer's disease (AD). The purpose of this pilot study was to test the impact of 6-month cycling on AD symptoms in community-dwelling older adults with mild-to-moderate AD, using a single-group, repeated-measures design (n = 26). AD symptoms...

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Detalles Bibliográficos
Autores principales: Yu, Fang, Thomas, William, Nelson, Nathaniel W., Bronas, Ulf G., Dysken, Maurice, Wyman, Jean F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696627/
https://www.ncbi.nlm.nih.gov/pubmed/24652914
http://dx.doi.org/10.1177/0733464813512895
Descripción
Sumario:Little is known about how aerobic exercise affects Alzheimer's disease (AD). The purpose of this pilot study was to test the impact of 6-month cycling on AD symptoms in community-dwelling older adults with mild-to-moderate AD, using a single-group, repeated-measures design (n = 26). AD symptoms were measured with the AD Assessment Scale–Cognitive (ADAS-Cog), Disability in AD (DAD), and Neuropsychiatric Inventory–Caregiver (NPI-Q) scales at baseline, 3 and 6 months. Data were analyzed using mixed linear models. The ADAS-Cog, DAD, and NPI-Q severity scores remained unchanged over the 6-month period, while caregiver distress decreased 40% (p < .05). We conclude that aerobic exercise may reduce AD symptoms and appears effective in decreasing caregiver distress. Further randomized controlled trials are needed to examine the effects of aerobic exercise in AD.

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