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Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms
Little is known about how aerobic exercise affects Alzheimer's disease (AD). The purpose of this pilot study was to test the impact of 6-month cycling on AD symptoms in community-dwelling older adults with mild-to-moderate AD, using a single-group, repeated-measures design (n = 26). AD symptoms...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696627/ https://www.ncbi.nlm.nih.gov/pubmed/24652914 http://dx.doi.org/10.1177/0733464813512895 |
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author | Yu, Fang Thomas, William Nelson, Nathaniel W. Bronas, Ulf G. Dysken, Maurice Wyman, Jean F. |
author_facet | Yu, Fang Thomas, William Nelson, Nathaniel W. Bronas, Ulf G. Dysken, Maurice Wyman, Jean F. |
author_sort | Yu, Fang |
collection | PubMed |
description | Little is known about how aerobic exercise affects Alzheimer's disease (AD). The purpose of this pilot study was to test the impact of 6-month cycling on AD symptoms in community-dwelling older adults with mild-to-moderate AD, using a single-group, repeated-measures design (n = 26). AD symptoms were measured with the AD Assessment Scale–Cognitive (ADAS-Cog), Disability in AD (DAD), and Neuropsychiatric Inventory–Caregiver (NPI-Q) scales at baseline, 3 and 6 months. Data were analyzed using mixed linear models. The ADAS-Cog, DAD, and NPI-Q severity scores remained unchanged over the 6-month period, while caregiver distress decreased 40% (p < .05). We conclude that aerobic exercise may reduce AD symptoms and appears effective in decreasing caregiver distress. Further randomized controlled trials are needed to examine the effects of aerobic exercise in AD. |
format | Online Article Text |
id | pubmed-5696627 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
record_format | MEDLINE/PubMed |
spelling | pubmed-56966272017-11-21 Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms Yu, Fang Thomas, William Nelson, Nathaniel W. Bronas, Ulf G. Dysken, Maurice Wyman, Jean F. J Appl Gerontol Article Little is known about how aerobic exercise affects Alzheimer's disease (AD). The purpose of this pilot study was to test the impact of 6-month cycling on AD symptoms in community-dwelling older adults with mild-to-moderate AD, using a single-group, repeated-measures design (n = 26). AD symptoms were measured with the AD Assessment Scale–Cognitive (ADAS-Cog), Disability in AD (DAD), and Neuropsychiatric Inventory–Caregiver (NPI-Q) scales at baseline, 3 and 6 months. Data were analyzed using mixed linear models. The ADAS-Cog, DAD, and NPI-Q severity scores remained unchanged over the 6-month period, while caregiver distress decreased 40% (p < .05). We conclude that aerobic exercise may reduce AD symptoms and appears effective in decreasing caregiver distress. Further randomized controlled trials are needed to examine the effects of aerobic exercise in AD. 2013-12-11 2015-06 /pmc/articles/PMC5696627/ /pubmed/24652914 http://dx.doi.org/10.1177/0733464813512895 Text en http://creativecommons.org/licenses/by/2.0/ Reprints and permissions: sagepub.com/journalsPermissions.nav |
spellingShingle | Article Yu, Fang Thomas, William Nelson, Nathaniel W. Bronas, Ulf G. Dysken, Maurice Wyman, Jean F. Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms |
title | Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms |
title_full | Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms |
title_fullStr | Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms |
title_full_unstemmed | Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms |
title_short | Impact of 6-Month Aerobic Exercise on Alzheimer's Symptoms |
title_sort | impact of 6-month aerobic exercise on alzheimer's symptoms |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696627/ https://www.ncbi.nlm.nih.gov/pubmed/24652914 http://dx.doi.org/10.1177/0733464813512895 |
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