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Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration

OBJECTIVES: To investigate whether serum neurofilament light (NfL) concentration is increased in familial Alzheimer disease (FAD), both pre and post symptom onset, and whether it is associated with markers of disease stage and severity. METHODS: We recruited 48 individuals from families with PSEN1 o...

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Detalles Bibliográficos
Autores principales:	Weston, Philip S.J., Poole, Teresa, Ryan, Natalie S., Nair, Akshay, Liang, Yuying, Macpherson, Kirsty, Druyeh, Ronald, Malone, Ian B., Ahsan, R. Laila, Pemberton, Hugh, Klimova, Jana, Mead, Simon, Blennow, Kaj, Rossor, Martin N., Schott, Jonathan M., Zetterberg, Henrik, Fox, Nick C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696646/ https://www.ncbi.nlm.nih.gov/pubmed/29070659 http://dx.doi.org/10.1212/WNL.0000000000004667

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