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A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage
[Image: see text] The bacterial SOS stress-response pathway is a pro-mutagenic DNA repair system that mediates bacterial survival and adaptation to genotoxic stressors, including antibiotics and UV light. The SOS pathway is composed of a network of genes under the control of the transcriptional repr...
Autores principales: | Kubiak, Jeffrey M., Culyba, Matthew J., Liu, Monica Yun, Mo, Charlie Y., Goulian, Mark, Kohli, Rahul M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696648/ https://www.ncbi.nlm.nih.gov/pubmed/28826208 http://dx.doi.org/10.1021/acssynbio.7b00108 |
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