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Clinicopathological Study of Pediatric Posterior Fossa Tumors

CONTEXT: Brain tumor is one of the most devastating forms of human illness, especially when occurring in the posterior fossa and involving the brainstem. Tumors in the posterior fossa are considered some of the most critical brain lesions. This is primarily due to the limited space within the poster...

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Detalles Bibliográficos
Autores principales: Prasad, Kadali Satya Vara, Ravi, D., Pallikonda, Vijay, Raman, Bhavana Venkata Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696661/
https://www.ncbi.nlm.nih.gov/pubmed/29204199
http://dx.doi.org/10.4103/jpn.JPN_113_16
Descripción
Sumario:CONTEXT: Brain tumor is one of the most devastating forms of human illness, especially when occurring in the posterior fossa and involving the brainstem. Tumors in the posterior fossa are considered some of the most critical brain lesions. This is primarily due to the limited space within the posterior fossa, as well as the potential involvement of the vital brainstem nuclei. AIMS: The aim of this study is to analyze the incidence, clinical features, surgical outcome, complications, and prognosis in a series of 37 pediatric patients with posterior fossa tumors who underwent surgery between September 2012 and January 2015 from the Department of Neurosurgery, King George Hospital, Visakhapatnam (both prospective and retrospective study). MATERIALS AND METHODS: A series of 37 cases were treated by the Department of Neurosurgery, King George Hospital, between August 2012 and January 2015. RESULTS: Posterior fossa tumors are predominantly seen in children with a peak incidence in the first decade. The most common presenting symptoms are raised intracranial pressure with headache and vomiting. Majority of the tumors are medulloblastomas, ependymomas, and cerebellar astrocytomas. The most common location is the cerebellar vermis, followed by the cerebellar hemispheres, followed by the forth ventricle and then the brainstem.