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Evaluation of the effect of a floxed Neo cassette within the dystroglycan (Dag1) gene
OBJECTIVE: Dystroglycan (DG) is an adhesion complex formed by two subunits, α-DG and β-DG. In skeletal muscle, DG is part of the dystrophin-glycoprotein complex that is crucial for sarcolemma stability and it is involved in a plethora of muscular dystrophy phenotypes. Due to the important role playe...
Autores principales: | Sciandra, Francesca, Scicchitano, Bianca Maria, Signorino, Giulia, Bigotti, Maria Giulia, Tavazzi, Barbara, Lombardi, Francesca, Bozzi, Manuela, Sica, Gigliola, Giardina, Bruno, Blaess, Sandra, Brancaccio, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696793/ https://www.ncbi.nlm.nih.gov/pubmed/29157305 http://dx.doi.org/10.1186/s13104-017-2926-9 |
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