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Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

BACKGROUND: Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron disorders. Effective therapeutic strategies are an unmet need for these disorders. Polyphenols, such as quercetin and resveratrol, are plant-derived compounds th...

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Detalles Bibliográficos
Autores principales:	Lazo-Gomez, Rafael, Tapia, Ricardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697078/ https://www.ncbi.nlm.nih.gov/pubmed/29201361 http://dx.doi.org/10.1186/s40035-017-0102-8

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