Cargando…
A validated antibody panel for the characterization of tau post-translational modifications
BACKGROUND: Tau is a microtubule-binding protein, which is subject to various post-translational modifications (PTMs) including phosphorylation, methylation, acetylation, glycosylation, nitration, sumoylation and truncation. Aberrant PTMs such as hyperphosphorylation result in tau aggregation and th...
Autores principales: | Ercan, Ebru, Eid, Sameh, Weber, Christian, Kowalski, Alexandra, Bichmann, Maria, Behrendt, Annika, Matthes, Frank, Krauss, Sybille, Reinhardt, Peter, Fulle, Simone, Ehrnhoefer, Dagmar E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697095/ https://www.ncbi.nlm.nih.gov/pubmed/29157277 http://dx.doi.org/10.1186/s13024-017-0229-1 |
Ejemplares similares
-
A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain
por: Ercan-Herbst, Ebru, et al.
Publicado: (2019) -
SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s disease
por: Bichmann, Maria, et al.
Publicado: (2021) -
Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates
por: Limorenko, Galina, et al.
Publicado: (2023) -
Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
por: Schweiger, Susann, et al.
Publicado: (2017) -
Regulation of mRNA Translation by MID1: A Common Mechanism of Expanded CAG Repeat RNAs
por: Griesche, Nadine, et al.
Publicado: (2016)