A 6‐bp Deletion Variant in a Novel Canine Glutathione‐S‐Transferase Gene (GSTT5) Leads to Loss of Enzyme Function

OBJECTIVES: Glutathione‐S‐transferases (GSTs) detoxify reactive xenobiotics, and defective GST gene polymorphisms increase cancer risk in humans. A low activity GST‐theta variant was previously found in research beagles. The purpose of our study was to determine the molecular basis for this phenotyp...

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Detalles Bibliográficos
Autores principales: Craft, S., Ekena, J., Sacco, J., Luethcke, K., Trepanier, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697189/
https://www.ncbi.nlm.nih.gov/pubmed/29105159
http://dx.doi.org/10.1111/jvim.14861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697189/
https://www.ncbi.nlm.nih.gov/pubmed/29105159
http://dx.doi.org/10.1111/jvim.14861

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