Structural characterisation of the capsular polysaccharide expressed by Burkholderia thailandensis strain E555:: wbiI (pKnock-KmR) and assessment of the significance of the 2-O-acetyl group in immune protection

Burkholderia pseudomallei and its close relative B. mallei are human pathogens that are classified as Tier 1 bio-threat agents. Both organisms have previously been shown to constitutively produce a capsular polysaccharide (CPS) that is both a virulence determinant and protective antigen. Extraction...

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Detalles Bibliográficos
Autores principales: Bayliss, Marc, Donaldson, Matthew I., Nepogodiev, Sergey A., Pergolizzi, Giulia, Scott, Andrew E., Harmer, Nicholas J., Field, Robert A., Prior, Joann L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697523/
https://www.ncbi.nlm.nih.gov/pubmed/29024844
http://dx.doi.org/10.1016/j.carres.2017.09.011

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