Human neonatal thymectomy induces altered B‐cell responses and autoreactivity

An association between T‐cell lymphopenia and autoimmunity has long been proposed, but it remains to be elucidated whether T‐cell lymphopenia affects B‐cell responses to autoantigens. Human neonatal thymectomy (Tx) results in a decrease in T‐cell numbers and we used this model to study the developme...

Descripción completa

Detalles Bibliográficos
Autores principales: van den Broek, Theo, Madi, Asaf, Delemarre, Eveline M., Schadenberg, Alvin W. L., Tesselaar, Kiki, Borghans, José A. M., Nierkens, Stefan, Redegeld, Frank A., Otten, Henny G., Rossetti, Maura, Albani, Salvatore, Sorek, Rachel, Cohen, Irun R., Jansen, Nicolaas J. G., van Wijk, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Immunodeficiencies and autoimmunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697610/
https://www.ncbi.nlm.nih.gov/pubmed/28691750
http://dx.doi.org/10.1002/eji.201746971

Ejemplares similares

Ejemplares similares