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Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination

Myelin abnormalities are increasingly being recognized as an important component of a number of neurologic developmental disorders. The integration of many signaling pathways and cell types are critical for correct myelinogenesis. The PI3-K and mechanistic target of rapamycin (mTOR) pathways have be...

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Detalles Bibliográficos
Autores principales:	Grier, Mark D., West, Kathryn L., Kelm, Nathaniel D., Fu, Cary, Does, Mark D., Parker, Brittany, McBrier, Eleanor, Lagrange, Andre H., Ess, Kevin C., Carson, Robert P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697806/ https://www.ncbi.nlm.nih.gov/pubmed/29161318 http://dx.doi.org/10.1371/journal.pone.0188417

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