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Transcriptome analysis of plasmid-induced genes sheds light on the role of type I IFN as adjuvant in DNA vaccine against infectious salmon anemia virus

A previous study showed that a plasmid expressing IFNa (pIFNa) strongly enhanced protection and antibody production of a DNA vaccine against infectious salmon anemia virus (ISAV) in Atlantic salmon. The vaccine consisted of a plasmid (pHE) expressing the virus hemagglutinin-esterase as an antigen. T...

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Detalles Bibliográficos
Autores principales:	Sobhkhez, Mehrdad, Krasnov, Aleksej, Chang, Chia Jung, Robertsen, Børre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697855/ https://www.ncbi.nlm.nih.gov/pubmed/29161315 http://dx.doi.org/10.1371/journal.pone.0188456

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