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Le déficit immunitaire commun variable à révélation tardive par des manifestations digestives: à propos d’un cas

Common Variable Immune Deficiency (CVID) is rare. It is a constitutional deficit of humoral immunity characterized by recurrent bacterial infections and by increased frequency of tumors, autoimmune or granulomatous diseases. Gastrointestinal manifestations are very variable and sometimes reveal comm...

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Detalles Bibliográficos
Autores principales: Ezzaitouni, Fatima, Thiyfa, Youssef, Tahiri, Mohamed, Haddad, Fouad, Hliwa, Wafaa, Bellabah, Ahmed, Badre, Wafaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697992/
https://www.ncbi.nlm.nih.gov/pubmed/29184600
http://dx.doi.org/10.11604/pamj.2017.28.48.12049
Descripción
Sumario:Common Variable Immune Deficiency (CVID) is rare. It is a constitutional deficit of humoral immunity characterized by recurrent bacterial infections and by increased frequency of tumors, autoimmune or granulomatous diseases. Gastrointestinal manifestations are very variable and sometimes reveal common variable immune deficiency. We report the case of a 31-year old patient with a history of childhood recurrent respiratory infections complicated by bronchiectasis and with a 3-year history of recurrent glairy diarrhea. Etiological balance was in favor of CVID with autoimmune manifestation (vitiligo). Patient’s treatment was based on monthly immunoglobulin (Ig) infusions with favorable outcome at 2-year follow-up.