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Molecular engineering and plant expression of an immunoglobulin heavy chain scaffold for delivery of a dengue vaccine candidate

In order to enhance vaccine uptake by the immune cells in vivo, molecular engineering approach was employed to construct a polymeric immunoglobulin G scaffold (PIGS) that incorporates multiple copies of an antigen and targets the Fc gamma receptors on antigen‐presenting cells. These self‐adjuvanting...

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Detalles Bibliográficos
Autores principales:	Kim, Mi‐Young, Van Dolleweerd, Craig, Copland, Alastair, Paul, Matthew John, Hofmann, Sven, Webster, Gina R., Julik, Emily, Ceballos‐Olvera, Ivonne, Reyes‐del Valle, Jorge, Yang, Moon‐Sik, Jang, Yong‐Suk, Reljic, Rajko, Ma, Julian K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698049/ https://www.ncbi.nlm.nih.gov/pubmed/28421694 http://dx.doi.org/10.1111/pbi.12741

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