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Single-molecule visualization of conformational changes and substrate transport in the vitamin B(12) ABC importer BtuCD-F
ATP-binding cassette (ABC) transporters form the largest class of active membrane transport proteins. Binding and hydrolysis of ATP by their highly conserved nucleotide-binding domains drive conformational changes of the complex that mediate transport of substrate across the membrane. The vitamin B(...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698293/ https://www.ncbi.nlm.nih.gov/pubmed/29162829 http://dx.doi.org/10.1038/s41467-017-01815-7 |