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Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
This retrospective study investigated whether the volume or density of the thrombus is predictive of recanalization in stent retriever (SR) treatment. Consecutive patients treated with SR thrombectomy as the first endovascular modality were enrolled. The thrombus volume and density were measured on...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698357/ https://www.ncbi.nlm.nih.gov/pubmed/29162921 http://dx.doi.org/10.1038/s41598-017-16274-9 |
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author | Baek, Jang-Hyun Yoo, Joonsang Song, Dongbeom Kim, Young Dae Nam, Hyo Suk Kim, Byung Moon Kim, Dong Joon Lee, Hye Sun Heo, Ji Hoe |
author_facet | Baek, Jang-Hyun Yoo, Joonsang Song, Dongbeom Kim, Young Dae Nam, Hyo Suk Kim, Byung Moon Kim, Dong Joon Lee, Hye Sun Heo, Ji Hoe |
author_sort | Baek, Jang-Hyun |
collection | PubMed |
description | This retrospective study investigated whether the volume or density of the thrombus is predictive of recanalization in stent retriever (SR) treatment. Consecutive patients treated with SR thrombectomy as the first endovascular modality were enrolled. The thrombus volume and density were measured on thin-section noncontrast computed tomography using 3-dimensional software. The patients were grouped by recanalization status and the number of SR passes. Among 165 patients, recanalization was achieved with the first pass in 68 (50.0%), 2–3 passes in 43 (31.6%), and ≥4 passes in 25 (18.4%) patients. The thrombus volume was smaller in patients with (107.5 mm(3)) than without (173.7 mm(3), p = 0.025) recanalization, and tended to be larger with increasing number of passes (p for trend = 0.001). The thrombus volume was an independent predictor of first-pass recanalization (odds ratio 0.93 per 10 mm(3), 95% confidence interval 0.89–0.97). However, the thrombus density was not associated with recanalization success. Recanalization within 3 passes was associated with a favorable outcome. In conclusion, the thrombus volume was significantly related to recanalization in SR thrombectomy. Measuring the thrombus volume was particularly predictive of first-pass recanalization, which was associated with a higher likelihood of a favorable outcome. |
format | Online Article Text |
id | pubmed-5698357 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-56983572017-11-29 Predictive value of thrombus volume for recanalization in stent retriever thrombectomy Baek, Jang-Hyun Yoo, Joonsang Song, Dongbeom Kim, Young Dae Nam, Hyo Suk Kim, Byung Moon Kim, Dong Joon Lee, Hye Sun Heo, Ji Hoe Sci Rep Article This retrospective study investigated whether the volume or density of the thrombus is predictive of recanalization in stent retriever (SR) treatment. Consecutive patients treated with SR thrombectomy as the first endovascular modality were enrolled. The thrombus volume and density were measured on thin-section noncontrast computed tomography using 3-dimensional software. The patients were grouped by recanalization status and the number of SR passes. Among 165 patients, recanalization was achieved with the first pass in 68 (50.0%), 2–3 passes in 43 (31.6%), and ≥4 passes in 25 (18.4%) patients. The thrombus volume was smaller in patients with (107.5 mm(3)) than without (173.7 mm(3), p = 0.025) recanalization, and tended to be larger with increasing number of passes (p for trend = 0.001). The thrombus volume was an independent predictor of first-pass recanalization (odds ratio 0.93 per 10 mm(3), 95% confidence interval 0.89–0.97). However, the thrombus density was not associated with recanalization success. Recanalization within 3 passes was associated with a favorable outcome. In conclusion, the thrombus volume was significantly related to recanalization in SR thrombectomy. Measuring the thrombus volume was particularly predictive of first-pass recanalization, which was associated with a higher likelihood of a favorable outcome. Nature Publishing Group UK 2017-11-21 /pmc/articles/PMC5698357/ /pubmed/29162921 http://dx.doi.org/10.1038/s41598-017-16274-9 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Baek, Jang-Hyun Yoo, Joonsang Song, Dongbeom Kim, Young Dae Nam, Hyo Suk Kim, Byung Moon Kim, Dong Joon Lee, Hye Sun Heo, Ji Hoe Predictive value of thrombus volume for recanalization in stent retriever thrombectomy |
title | Predictive value of thrombus volume for recanalization in stent retriever thrombectomy |
title_full | Predictive value of thrombus volume for recanalization in stent retriever thrombectomy |
title_fullStr | Predictive value of thrombus volume for recanalization in stent retriever thrombectomy |
title_full_unstemmed | Predictive value of thrombus volume for recanalization in stent retriever thrombectomy |
title_short | Predictive value of thrombus volume for recanalization in stent retriever thrombectomy |
title_sort | predictive value of thrombus volume for recanalization in stent retriever thrombectomy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698357/ https://www.ncbi.nlm.nih.gov/pubmed/29162921 http://dx.doi.org/10.1038/s41598-017-16274-9 |
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