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Predictive value of thrombus volume for recanalization in stent retriever thrombectomy

This retrospective study investigated whether the volume or density of the thrombus is predictive of recanalization in stent retriever (SR) treatment. Consecutive patients treated with SR thrombectomy as the first endovascular modality were enrolled. The thrombus volume and density were measured on...

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Autores principales: Baek, Jang-Hyun, Yoo, Joonsang, Song, Dongbeom, Kim, Young Dae, Nam, Hyo Suk, Kim, Byung Moon, Kim, Dong Joon, Lee, Hye Sun, Heo, Ji Hoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698357/
https://www.ncbi.nlm.nih.gov/pubmed/29162921
http://dx.doi.org/10.1038/s41598-017-16274-9
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author Baek, Jang-Hyun
Yoo, Joonsang
Song, Dongbeom
Kim, Young Dae
Nam, Hyo Suk
Kim, Byung Moon
Kim, Dong Joon
Lee, Hye Sun
Heo, Ji Hoe
author_facet Baek, Jang-Hyun
Yoo, Joonsang
Song, Dongbeom
Kim, Young Dae
Nam, Hyo Suk
Kim, Byung Moon
Kim, Dong Joon
Lee, Hye Sun
Heo, Ji Hoe
author_sort Baek, Jang-Hyun
collection PubMed
description This retrospective study investigated whether the volume or density of the thrombus is predictive of recanalization in stent retriever (SR) treatment. Consecutive patients treated with SR thrombectomy as the first endovascular modality were enrolled. The thrombus volume and density were measured on thin-section noncontrast computed tomography using 3-dimensional software. The patients were grouped by recanalization status and the number of SR passes. Among 165 patients, recanalization was achieved with the first pass in 68 (50.0%), 2–3 passes in 43 (31.6%), and ≥4 passes in 25 (18.4%) patients. The thrombus volume was smaller in patients with (107.5 mm(3)) than without (173.7 mm(3), p = 0.025) recanalization, and tended to be larger with increasing number of passes (p for trend = 0.001). The thrombus volume was an independent predictor of first-pass recanalization (odds ratio 0.93 per 10 mm(3), 95% confidence interval 0.89–0.97). However, the thrombus density was not associated with recanalization success. Recanalization within 3 passes was associated with a favorable outcome. In conclusion, the thrombus volume was significantly related to recanalization in SR thrombectomy. Measuring the thrombus volume was particularly predictive of first-pass recanalization, which was associated with a higher likelihood of a favorable outcome.
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spelling pubmed-56983572017-11-29 Predictive value of thrombus volume for recanalization in stent retriever thrombectomy Baek, Jang-Hyun Yoo, Joonsang Song, Dongbeom Kim, Young Dae Nam, Hyo Suk Kim, Byung Moon Kim, Dong Joon Lee, Hye Sun Heo, Ji Hoe Sci Rep Article This retrospective study investigated whether the volume or density of the thrombus is predictive of recanalization in stent retriever (SR) treatment. Consecutive patients treated with SR thrombectomy as the first endovascular modality were enrolled. The thrombus volume and density were measured on thin-section noncontrast computed tomography using 3-dimensional software. The patients were grouped by recanalization status and the number of SR passes. Among 165 patients, recanalization was achieved with the first pass in 68 (50.0%), 2–3 passes in 43 (31.6%), and ≥4 passes in 25 (18.4%) patients. The thrombus volume was smaller in patients with (107.5 mm(3)) than without (173.7 mm(3), p = 0.025) recanalization, and tended to be larger with increasing number of passes (p for trend = 0.001). The thrombus volume was an independent predictor of first-pass recanalization (odds ratio 0.93 per 10 mm(3), 95% confidence interval 0.89–0.97). However, the thrombus density was not associated with recanalization success. Recanalization within 3 passes was associated with a favorable outcome. In conclusion, the thrombus volume was significantly related to recanalization in SR thrombectomy. Measuring the thrombus volume was particularly predictive of first-pass recanalization, which was associated with a higher likelihood of a favorable outcome. Nature Publishing Group UK 2017-11-21 /pmc/articles/PMC5698357/ /pubmed/29162921 http://dx.doi.org/10.1038/s41598-017-16274-9 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Baek, Jang-Hyun
Yoo, Joonsang
Song, Dongbeom
Kim, Young Dae
Nam, Hyo Suk
Kim, Byung Moon
Kim, Dong Joon
Lee, Hye Sun
Heo, Ji Hoe
Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
title Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
title_full Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
title_fullStr Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
title_full_unstemmed Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
title_short Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
title_sort predictive value of thrombus volume for recanalization in stent retriever thrombectomy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698357/
https://www.ncbi.nlm.nih.gov/pubmed/29162921
http://dx.doi.org/10.1038/s41598-017-16274-9
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