Cargando…
Enzymatic Characterization of Fructose 1,6-Bisphosphatase II from Francisella tularensis, an Essential Enzyme for Pathogenesis
The glpX gene from Francisella tularensis encodes for the class II fructose 1,6-bisphosphatase (FBPaseII) enzyme. The glpX gene has been verified to be essential in F. tularensis, and the inactivation of this gene leads to impaired bacterial growth on gluconeogenic substrates. In the present work, w...
Autores principales: | Gutka, Hiten J., Wolf, Nina M., Bondoc, Jasper Marc G., Movahedzadeh, Farahnaz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698383/ https://www.ncbi.nlm.nih.gov/pubmed/28547120 http://dx.doi.org/10.1007/s12010-017-2512-6 |
Ejemplares similares
-
Structural and biochemical characterization of the class II fructose-1,6-bisphosphatase from Francisella tularensis
por: Selezneva, Anna I., et al.
Publicado: (2020) -
New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class
por: Selezneva, Anna I., et al.
Publicado: (2023) -
Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition
por: Wolf, Nina M., et al.
Publicado: (2018) -
Mutagenesis of threonine to serine in the active site of Mycobacterium tuberculosis fructose-1,6-bisphosphatase (Class II) retains partial enzyme activity
por: Bondoc, Jasper Marc G., et al.
Publicado: (2017) -
A two-step strategy for the complementation of M. tuberculosis mutants
por: Movahedzadeh, Farahnaz, et al.
Publicado: (2011)