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TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response
Adult neurogenesis persists in the rodent dentate gyrus and is stimulated by chronic treatment with conventional antidepressants through BDNF/TrkB signaling. Ketamine in low doses produces both rapid and sustained antidepressant effects in patients. Previous studies have shed light on post-transcrip...
Autores principales: | Ma, Zhenzhong, Zang, Tong, Birnbaum, Shari G., Wang, Zilai, Johnson, Jane E., Zhang, Chun-Li, Parada, Luis F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698402/ https://www.ncbi.nlm.nih.gov/pubmed/29162814 http://dx.doi.org/10.1038/s41467-017-01709-8 |
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