Cargando…

microRNA-449a modulates medullary thymic epithelial cell differentiation

Medullary thymic epithelial cells (mTECs) ectopically express a diversity of peripheral tissue-restricted antigens (PTAs) and provide unique cues for the expansion, maturation and selection of a repertoire of functionally diverse T lymphocytes. Genetic deletion of all mature microRNAs in thymic epit...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Pengfei, Zhang, Haohao, Sun, Xiaohua, Hu, Yiming, Jiang, Wenxia, Liu, Zhanjie, Liu, Sanhong, Zhang, Xiaoren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698406/
https://www.ncbi.nlm.nih.gov/pubmed/29162901
http://dx.doi.org/10.1038/s41598-017-16162-2