Shear Stress Regulates TRPV4 Channel Clustering and Translocation from Adherens Junctions to the Basal Membrane

Localized Ca(2+) influx via TRPV4 on the surface of endothelial cells greatly influences endothelial adaptation to blood flow, but how mechanical stress from blood flow controls TRPV4 integration into this physiological function is not fully understood. Here, we studied the spatial organization of T...

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Detalles Bibliográficos
Autores principales: Baratchi, Sara, Knoerzer, Markus, Khoshmanesh, Khashayar, Mitchell, Arnan, McIntyre, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698423/
https://www.ncbi.nlm.nih.gov/pubmed/29162902
http://dx.doi.org/10.1038/s41598-017-16276-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698423/
https://www.ncbi.nlm.nih.gov/pubmed/29162902
http://dx.doi.org/10.1038/s41598-017-16276-7

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