A library of chemically defined human N-glycans synthesized from microbial oligosaccharide precursors

Synthesis of homogenous glycans in quantitative yields represents a major bottleneck to the production of molecular tools for glycoscience, such as glycan microarrays, affinity resins, and reference standards. Here, we describe a combined biological/enzymatic synthesis that is capable of efficiently...

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Detalles Bibliográficos
Autores principales: Hamilton, Brian S., Wilson, Joshua D., Shumakovich, Marina A., Fisher, Adam C., Brooks, James C., Pontes, Alyssa, Naran, Radnaa, Heiss, Christian, Gao, Chao, Kardish, Robert, Heimburg-Molinaro, Jamie, Azadi, Parastoo, Cummings, Richard D., Merritt, Judith H., DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698433/
https://www.ncbi.nlm.nih.gov/pubmed/29162910
http://dx.doi.org/10.1038/s41598-017-15891-8

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