A small molecule screen to identify regulators of let-7 targets

The let-7 family of miRNAs has been shown to be crucial in many aspects of biology, from the regulation of developmental timing to cancer. The available methods to regulate this family of miRNAs have so far been mostly genetic and therefore not easily performed experimentally. Here, we describe a sm...

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Detalles Bibliográficos
Autores principales: Cinkornpumin, J., Roos, M., Nguyen, L., Liu, Xiaoguang, Gaeta, X., Lin, S., Chan, D. N., Liu, A., Gregory, R. I., Jung, M., Chute, J., Zhu, H., Lowry, W. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698460/
https://www.ncbi.nlm.nih.gov/pubmed/29162914
http://dx.doi.org/10.1038/s41598-017-16258-9

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