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mDia1 senses both force and torque during F-actin filament polymerization

Formins, an important family of force-bearing actin-polymerizing factors, function as homodimers that bind with the barbed end of actin filaments through a ring-like structure assembled from dimerized FH2 domains. It has been hypothesized that force applied to formin may facilitate transition of the...

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Detalles Bibliográficos
Autores principales: Yu, Miao, Yuan, Xin, Lu, Chen, Le, Shimin, Kawamura, Ryo, Efremov, Artem K., Zhao, Zhihai, Kozlov, Michael M., Sheetz, Michael, Bershadsky, Alexander, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698482/
https://www.ncbi.nlm.nih.gov/pubmed/29162803
http://dx.doi.org/10.1038/s41467-017-01745-4