Circulating tumor cells in head and neck cancer: A review

Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness....

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Detalles Bibliográficos
Autores principales: McMullen, Kyle P., Chalmers, Jeffrey J., Lang, Jas C., Kumar, Pawan, Jatana, Kris R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Innovative Diagnostic Tool
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698518/
https://www.ncbi.nlm.nih.gov/pubmed/29204555
http://dx.doi.org/10.1016/j.wjorl.2016.05.003
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author McMullen, Kyle P.
Chalmers, Jeffrey J.
Lang, Jas C.
Kumar, Pawan
Jatana, Kris R.
author_facet McMullen, Kyle P.
Chalmers, Jeffrey J.
Lang, Jas C.
Kumar, Pawan
Jatana, Kris R.
author_sort McMullen, Kyle P.
collection PubMed
description Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic disease, response to treatment, and surveillance in head and neck squamous cell carcinoma. In this article, techniques of CTC detection, applications of CTC technology, and outcomes of HNSCC patients will be discussed.
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spelling pubmed-56985182017-12-04 Circulating tumor cells in head and neck cancer: A review McMullen, Kyle P. Chalmers, Jeffrey J. Lang, Jas C. Kumar, Pawan Jatana, Kris R. World J Otorhinolaryngol Head Neck Surg Innovative Diagnostic Tool Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic disease, response to treatment, and surveillance in head and neck squamous cell carcinoma. In this article, techniques of CTC detection, applications of CTC technology, and outcomes of HNSCC patients will be discussed. KeAi Publishing 2016-07-21 /pmc/articles/PMC5698518/ /pubmed/29204555 http://dx.doi.org/10.1016/j.wjorl.2016.05.003 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Innovative Diagnostic Tool
McMullen, Kyle P.
Chalmers, Jeffrey J.
Lang, Jas C.
Kumar, Pawan
Jatana, Kris R.
Circulating tumor cells in head and neck cancer: A review
title Circulating tumor cells in head and neck cancer: A review
title_full Circulating tumor cells in head and neck cancer: A review
title_fullStr Circulating tumor cells in head and neck cancer: A review
title_full_unstemmed Circulating tumor cells in head and neck cancer: A review
title_short Circulating tumor cells in head and neck cancer: A review
title_sort circulating tumor cells in head and neck cancer: a review
topic Innovative Diagnostic Tool
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698518/
https://www.ncbi.nlm.nih.gov/pubmed/29204555
http://dx.doi.org/10.1016/j.wjorl.2016.05.003
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