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Population pharmacokinetic meta‐analysis of ramucirumab in cancer patients

AIMS: Ramucirumab is a human IgG1 monoclonal antibody that specifically binds vascular endothelial growth factor receptor‐2 (VEGFR‐2) and blocks binding of VEGF‐A, VEGF‐C and VEGF‐D. The objective of the analysis was to characterize the clinical pharmacology profile of ramucirumab using a population...

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Detalles Bibliográficos
Autores principales:	O'Brien, Lisa, Westwood, Paul, Gao, Ling, Heathman, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Pharmacokinetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698573/ https://www.ncbi.nlm.nih.gov/pubmed/28833321 http://dx.doi.org/10.1111/bcp.13403

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