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Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin–piperaquine in healthy volunteers

AIMS: The aims of the present study were to evaluate the pharmacokinetic properties of dihydroartemisinin (DHA) and piperaquine, potential drug–drug interactions with concomitant primaquine treatment, and piperaquine effects on the electrocardiogram in healthy volunteers. METHODS: The population pha...

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Detalles Bibliográficos
Autores principales:	Chotsiri, Palang, Wattanakul, Thanaporn, Hoglund, Richard M., Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Blessborn, Daniel, Jittamala, Podjanee, White, Nicholas J., Day, Nicholas P.J., Tarning, Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Pharmacokinetic Dynamic Relationships
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698590/ https://www.ncbi.nlm.nih.gov/pubmed/28695570 http://dx.doi.org/10.1111/bcp.13372

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