Cargando…

FXR controls CHOP expression in steatohepatitis

The farnesoid X receptor (FXR) and C/EBP homologous protein (CHOP) have critical functions in hepatic lipid metabolism. Here, we aimed to explore a potential relationship between FXR and CHOP. We fed wild‐type (WT) and FXR KO mice a MCD diet (model of steatohepatitis) and found that Chop mRNA expres...

Descripción completa

Detalles Bibliográficos
Autores principales: Fuchs, Claudia D., Claudel, Thierry, Scharnagl, Hubert, Stojakovic, Tatjana, Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698708/
https://www.ncbi.nlm.nih.gov/pubmed/28895119
http://dx.doi.org/10.1002/1873-3468.12845