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FXR controls CHOP expression in steatohepatitis
The farnesoid X receptor (FXR) and C/EBP homologous protein (CHOP) have critical functions in hepatic lipid metabolism. Here, we aimed to explore a potential relationship between FXR and CHOP. We fed wild‐type (WT) and FXR KO mice a MCD diet (model of steatohepatitis) and found that Chop mRNA expres...
Autores principales: | Fuchs, Claudia D., Claudel, Thierry, Scharnagl, Hubert, Stojakovic, Tatjana, Trauner, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698708/ https://www.ncbi.nlm.nih.gov/pubmed/28895119 http://dx.doi.org/10.1002/1873-3468.12845 |
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