Cargando…
Escherichia coli “TatExpress” strains super‐secrete human growth hormone into the bacterial periplasm by the Tat pathway
Numerous high‐value proteins are secreted into the Escherichia coli periplasm by the General Secretory (Sec) pathway, but Sec‐based production chassis cannot handle many potential target proteins. The Tat pathway offers a promising alternative because it transports fully folded proteins; however, yi...
Autores principales: | Browning, Douglas F., Richards, Kirsty L., Peswani, Amber R., Roobol, Jo, Busby, Stephen J.W., Robinson, Colin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698719/ https://www.ncbi.nlm.nih.gov/pubmed/28842980 http://dx.doi.org/10.1002/bit.26434 |
Ejemplares similares
-
Escherichia coli “TatExpress” strains export several g/L human growth hormone to the periplasm by the Tat pathway
por: Guerrero Montero, Isabel, et al.
Publicado: (2019) -
Highly efficient export of a disulfide‐bonded protein to the periplasm and medium by the Tat pathway using CyDisCo in Escherichia coli
por: Arauzo‐Aguilera, Klaudia, et al.
Publicado: (2023) -
Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli
por: Habersetzer, Johann, et al.
Publicado: (2017) -
TatA and TatB generate a hydrophobic mismatch important for the function and assembly of the Tat translocon in Escherichia coli
por: Mehner-Breitfeld, Denise, et al.
Publicado: (2022) -
Characterization of a TatA/TatB binding site on the TatC component of the Escherichia coli twin arginine translocase
por: Severi, Emmanuele, et al.
Publicado: (2023)