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The PAC‐SYM questionnaire for chronic constipation: defining the minimal important difference
BACKGROUND: The Patient Assessment of Constipation‐Symptoms (PAC‐SYM) questionnaire is frequently used in clinical trials of constipation. However, the threshold for reduction in total PAC‐SYM score used to define a clinical response on this 0‐4 point scale has not undergone formal appraisal, and it...
Autores principales: | Yiannakou, Y., Tack, J., Piessevaux, H., Dubois, D., Quigley, E. M. M., Ke, M. Y., Da Silva, S., Joseph, A., Kerstens, R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698746/ https://www.ncbi.nlm.nih.gov/pubmed/28983926 http://dx.doi.org/10.1111/apt.14349 |
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