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Transient Receptor Potential Melastatin 2 Negatively Regulates LPS-ATP-Induced Caspase-1-Dependent Pyroptosis of Bone Marrow-Derived Macrophage by Modulating ROS Production

BACKGROUND: Pyroptosis, a new form of cell death, which has special morphological characteristics, depends on caspase-1 activation and occupies an important role in inflammatory immune diseases and ischemia-reperfusion injury. ROS is a common activator of NLR/caspase-1. Transient receptor potential...

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Detalles Bibliográficos
Autores principales:	Wang, Haihong, Zhou, Xinyi, Li, Hui, Qian, Xiaowei, Wang, Yan, Ma, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698788/ https://www.ncbi.nlm.nih.gov/pubmed/29250536 http://dx.doi.org/10.1155/2017/2975648

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