Cargando…

Cytotoxicity and Proapoptotic Effects of Allium atroviolaceum Flower Extract by Modulating Cell Cycle Arrest and Caspase-Dependent and p53-Independent Pathway in Breast Cancer Cell Lines

Breast cancer is the second leading cause of cancer death among women and despite significant advances in therapy, it remains a critical health problem worldwide. Allium atroviolaceum is an herbaceous plant, with limited information about the therapeutic capability. We aimed to study the anticancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khazaei, Somayeh, Abdul Hamid, Roslida, Ramachandran, Vasudevan, Mohd Esa, Norhaizan, Pandurangan, Ashok Kumar, Danazadeh, Fatemeh, Ismail, Patimah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698829/ https://www.ncbi.nlm.nih.gov/pubmed/29250124 http://dx.doi.org/10.1155/2017/1468957

Ejemplares similares

In vitro Antiproliferative and Apoptosis Inducing Effect of Allium atroviolaceum Bulb Extract on Breast, Cervical, and Liver Cancer Cells
por: Khazaei, Somayeh, et al.
Publicado: (2017)

Promotion of HepG2 cell apoptosis by flower of Allium atroviolaceum and the mechanism of action
por: Khazaei, S., et al.
Publicado: (2017)

Effect of hydroalcoholic Allium atroviolaceum L. on the pathology of testicular tissue in cyclophosphamide-treated mice
por: Shahrani, Mehrdad, et al.
Publicado: (2020)

Inositol-6 phosphate inhibits the mTOR pathway and induces autophagy-mediated death in HT-29 colon cancer cells
por: Pandurangan, Ashok Kumar, et al.
Publicado: (2018)

Pro-Apoptotic Effect of Rice Bran Inositol Hexaphosphate (IP(6)) on HT-29 Colorectal Cancer Cells
por: Shafie, Nurul Husna, et al.
Publicado: (2013)

Allicin Alleviates Dextran Sodium Sulfate- (DSS-) Induced Ulcerative Colitis in BALB/c Mice
por: Pandurangan, Ashok Kumar, et al.
Publicado: (2015)

Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice
por: Pandurangan, Ashok Kumar, et al.
Publicado: (2015)

Preventive Inositol Hexaphosphate Extracted from Rice Bran Inhibits Colorectal Cancer through Involvement of Wnt/β-Catenin and COX-2 Pathways
por: Shafie, Nurul Husna, et al.
Publicado: (2013)

Effects of the flower extract of Ixora coccinea Linn. On the meristematic cells of Allium Cepa
por: Latha, P.G., et al.
Publicado: (1998)

Cytotoxic Steroidal Saponins from the Flowers of Allium leucanthum
por: Mskhiladze, Lasha, et al.
Publicado: (2008)

ROS-Mediated Mitochondrial Pathway is Required for Manilkara Zapota (L.) P. Royen Leaf Methanol Extract Inducing Apoptosis in the Modulation of Caspase Activation and EGFR/NF-κB Activities of HeLa Human Cervical Cancer Cells
por: Tan, Bee Ling, et al.
Publicado: (2018)

An Intrinsic Mitochondrial Pathway Is Required for Phytic Acid-Chitosan-Iron Oxide Nanocomposite (Phy-CS-MNP) to Induce G(0)/G(1) Cell Cycle Arrest and Apoptosis in the Human Colorectal Cancer (HT-29) Cell Line
por: Tan, Bee Ling, et al.
Publicado: (2018)

Erratum to “Expression Profiling of Genes Related to Endothelial Cells Biology in Patients with Type 2 Diabetes and Patients with Prediabetes”
por: Moradipoor, Sara, et al.
Publicado: (2017)

Antiproliferative Activity, Proapoptotic Effect, and Cell Cycle Arrest in Human Cancer Cells of Some Marine Natural Product Extract
por: Cui, Hong, et al.
Publicado: (2020)

Ectopically Expressed Perforin-1 Is Proapoptotic in Tumor Cell Lines by Increasing Caspase-3 Activity and the Nuclear Translocation of Cytochrome c
por: Wang, Li-Feng, et al.
Publicado: (2012)

The Effect of G. applanatum Crude Polysaccharide Extract on Proinflammatory Cytokines and Proapoptotic Caspases in HeLa Cell Line: An In Vitro Study
por: A'yun, Qurrotu, et al.
Publicado: (2023)

Analysis of renin-angiotensin aldosterone system gene polymorphisms in malaysian essential hypertensive and type 2 diabetic subjects
por: Ramachandran, Vasudevan, et al.
Publicado: (2009)

Water extract of brewers’ rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers’ rice-treated rats with azoxymethane-induced colon carcinogenesis
por: Tan, Bee Ling, et al.
Publicado: (2015)

Molecular and Functional Characterization of FLOWERING LOCUS T Homologs in Allium cepa
por: Manoharan, Ranjith Kumar, et al.
Publicado: (2016)

Chemical and Biological Investigations of Allium scorodoprasum L. Flower Extracts
por: Đorđevski, Nikoleta, et al.
Publicado: (2022)

Sustained release of anticancer agent phytic acid from its chitosan-coated magnetic nanoparticles for drug-delivery system
por: Barahuie, Farahnaz, et al.
Publicado: (2017)

Proapoptotic Role of Potassium Ions in Liver Cells
por: Xia, Zhenglin, et al.
Publicado: (2016)

Proapoptotic effect of endocannabinoids in prostate cancer cells
por: ORELLANA-SERRADELL, O., et al.
Publicado: (2015)

Garlic (Allium sativum)-derived SEVs inhibit cancer cell proliferation and induce caspase mediated apoptosis
por: Özkan, İrem, et al.
Publicado: (2021)

Antiangiogenic and Proapoptotic Activities of Atorvastatin and Ganoderma lucidum in Tumor Mouse Model via VEGF and Caspase-3 Pathways
por: El-Khashab, Iman Hesham
Publicado: (2021)

Phosphorylation of the Proapoptotic BH3-Only Protein Bid Primes Mitochondria for Apoptosis during Mitotic Arrest
por: Wang, Pengbo, et al.
Publicado: (2014)

Loss of the proapoptotic protein, Bim, breaks B cell anergy
por: Oliver, Paula M., et al.
Publicado: (2006)

Proapoptotic effects of novel pentabromobenzylisothioureas in human leukemia cell lines
por: Koronkiewicz, Mirosława, et al.
Publicado: (2011)

Involvement of proapoptotic genes in autophagic cell death induced by irradiation
por: Song, Jianrui, et al.
Publicado: (2017)

MEK–ERK-dependent multiple caspase activation by mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma cell death
por: Tomiyama, A, et al.
Publicado: (2010)

Antiproliferative and Proapoptotic Activities of Marine Sponge Hyrtios erectus Extract on Breast Carcinoma Cell Line (MCF-7)
por: Muthiyan, Ramachandran, et al.
Publicado: (2017)

Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein Bim(EL) and induces apoptosis
por: Lund, T, et al.
Publicado: (2005)

Proapoptotic role of nuclear clusterin in brain
por: Kim, Nayoung, et al.
Publicado: (2011)

New Steroidal Selenides as Proapoptotic Factors
por: Jastrzebska, Izabella, et al.
Publicado: (2023)

Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells
por: Peduto Eberl, L, et al.
Publicado: (2003)

Proapoptotic protein Bid is regulated by phosphorylation during anoikis and the cell cycle
por: Lindsay, J, et al.
Publicado: (2008)

Tipifarnib and tanespimycin show synergic proapoptotic activity in U937 cells
por: Krzykowska-Petitjean, Katarzyna, et al.
Publicado: (2011)

Polyphenols are responsible for the proapoptotic properties of pomegranate juice on leukemia cell lines
por: Dahlawi, Haytham, et al.
Publicado: (2013)

Antiproliferative and proapoptotic effects of DODAC/synthetic phosphoethanolamine on hepatocellular carcinoma cells
por: Luna, Arthur Cássio de Lima, et al.
Publicado: (2018)

Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells
por: Funakoshi-Tago, Megumi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jtrti9dr4knnv35nhrqucl007t