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Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism

[Image: see text] Many women consider botanical dietary supplements (BDSs) as safe alternatives to hormone therapy for menopausal symptoms. However, the effect of BDSs on breast cancer risk is largely unknown. In the estrogen chemical carcinogenesis pathway, P450 1B1 metabolizes estrogens to 4-hydro...

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Detalles Bibliográficos
Autores principales:	Dunlap, Tareisha L., Howell, Caitlin E., Mukand, Nita, Chen, Shao-Nong, Pauli, Guido F., Dietz, Birgit M., Bolton, Judy L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698877/ https://www.ncbi.nlm.nih.gov/pubmed/28985473 http://dx.doi.org/10.1021/acs.chemrestox.7b00237

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