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Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series
INTRODUCTION: Posterior reversible encephalopathy syndrome (PRES) is characterized by a range of clinico neuro radiological manifestation along with hypertension due to varied etiology. Contrary to its name, a small number of patients have residual neurological deficits. Patients with severe manifes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699006/ https://www.ncbi.nlm.nih.gov/pubmed/29279639 http://dx.doi.org/10.4103/ijccm.IJCCM_235_17 |
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author | Gokhale, Antara Kimona, Atheel Kantor, Sandeep Prakash, S. Manhas, Yogesh |
author_facet | Gokhale, Antara Kimona, Atheel Kantor, Sandeep Prakash, S. Manhas, Yogesh |
author_sort | Gokhale, Antara |
collection | PubMed |
description | INTRODUCTION: Posterior reversible encephalopathy syndrome (PRES) is characterized by a range of clinico neuro radiological manifestation along with hypertension due to varied etiology. Contrary to its name, a small number of patients have residual neurological deficits. Patients with severe manifestation of PRES may get admitted to the Intensive Care Unit (ICU) due to coma or status epilepticus. Small case series and large multicenter studies have been reported. MATERIALS AND METHODS: We report a single center series of ten cases admitted to ICU over a 5 year period in a tertiary care centre. We retrospectively analyzed patients, admitted to adult ICU with different etiologies, and diagnosed to have PRES. Outcome at discharge and at 90 days after ICU admission was noted. RESULT: The most common etiologies were medications. ICU admissions were mainly for uncontrolled hypertension, seizures, and low level of consciousness. All except one patient were ventilated. Four patients had residual neurological damage. CONCLUSION: Irrespective of the etiology, early control of blood pressure, and removal of precipitating factors is of paramount importance to prevent morbidity and mortality. Awareness about PRES among the intensivist is necessary to ensure early recognition and treatment. |
format | Online Article Text |
id | pubmed-5699006 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56990062017-12-26 Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series Gokhale, Antara Kimona, Atheel Kantor, Sandeep Prakash, S. Manhas, Yogesh Indian J Crit Care Med Brief Communication INTRODUCTION: Posterior reversible encephalopathy syndrome (PRES) is characterized by a range of clinico neuro radiological manifestation along with hypertension due to varied etiology. Contrary to its name, a small number of patients have residual neurological deficits. Patients with severe manifestation of PRES may get admitted to the Intensive Care Unit (ICU) due to coma or status epilepticus. Small case series and large multicenter studies have been reported. MATERIALS AND METHODS: We report a single center series of ten cases admitted to ICU over a 5 year period in a tertiary care centre. We retrospectively analyzed patients, admitted to adult ICU with different etiologies, and diagnosed to have PRES. Outcome at discharge and at 90 days after ICU admission was noted. RESULT: The most common etiologies were medications. ICU admissions were mainly for uncontrolled hypertension, seizures, and low level of consciousness. All except one patient were ventilated. Four patients had residual neurological damage. CONCLUSION: Irrespective of the etiology, early control of blood pressure, and removal of precipitating factors is of paramount importance to prevent morbidity and mortality. Awareness about PRES among the intensivist is necessary to ensure early recognition and treatment. Medknow Publications & Media Pvt Ltd 2017-11 /pmc/articles/PMC5699006/ /pubmed/29279639 http://dx.doi.org/10.4103/ijccm.IJCCM_235_17 Text en Copyright: © 2017 Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Brief Communication Gokhale, Antara Kimona, Atheel Kantor, Sandeep Prakash, S. Manhas, Yogesh Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series |
title | Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series |
title_full | Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series |
title_fullStr | Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series |
title_full_unstemmed | Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series |
title_short | Posterior Reversible Leukoencephalopathy Syndrome (PRES) in Intensive Care Unit – Case series |
title_sort | posterior reversible leukoencephalopathy syndrome (pres) in intensive care unit – case series |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699006/ https://www.ncbi.nlm.nih.gov/pubmed/29279639 http://dx.doi.org/10.4103/ijccm.IJCCM_235_17 |
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