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MPSR1 is a cytoplasmic PQC E3 ligase for eliminating emergent misfolded proteins in Arabidopsis thaliana

Ubiquitin E3 ligases are crucial for eliminating misfolded proteins before they form cytotoxic aggregates that threaten cell fitness and survival. However, it remains unclear how emerging misfolded proteins in the cytoplasm can be selectively recognized and eliminated by E3 ligases in plants. We fou...

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Detalles Bibliográficos
Autores principales: Kim, Jong Hum, Cho, Seok Keun, Oh, Tae Rin, Ryu, Moon Young, Yang, Seong Wook, Kim, Woo Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699081/
https://www.ncbi.nlm.nih.gov/pubmed/29087340
http://dx.doi.org/10.1073/pnas.1713574114