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Independent suppression of ribosomal +1 frameshifts by different tRNA anticodon loop modifications

Recently, a role for the anticodon wobble uridine modification 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U) has been revealed in the suppression of translational +1 frameshifts in Saccharomyces cerevisiae. Loss of either the mcm(5)U or s(2)U parts of the modification elevated +1 frameshift ra...

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Detalles Bibliográficos
Autores principales: Klassen, Roland, Bruch, Alexander, Schaffrath, Raffael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699549/
https://www.ncbi.nlm.nih.gov/pubmed/27937809
http://dx.doi.org/10.1080/15476286.2016.1267098

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