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Development of Dengue virus type 2 replicons capable of prolonged expression in host cells

BACKGROUND: As part of a program to develop a Dengue virus vaccine which avoids the deleterious effects of antibody dependent enhancement (ADE) of infection mediated by antibodies to Dengue virus structural proteins, we have begun to investigate the possibility of designing Dengue vaccines based on...

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Detalles Bibliográficos
Autores principales: Pang, Xiaowu, Zhang, Mingjie, Dayton, Andrew I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC56997/
https://www.ncbi.nlm.nih.gov/pubmed/11580862