MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner

Mitochondrial antiviral-signaling protein (MAVS) transmits signals from RIG-I-like receptors after RNA virus infections. However, the mechanism by which MAVS activates downstream components, such as TBK1 and IKKα/β, is unclear, although previous work suggests the involvement of NEMO or TBK1-binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Run, Jiang, Qifei, Zhou, Xiang, Wang, Chenguang, Guan, Yukun, Tao, Jianli, Xi, Jianzhong, Feng, Ji-Ming, Jiang, Zhengfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699845/
https://www.ncbi.nlm.nih.gov/pubmed/29125880
http://dx.doi.org/10.1371/journal.ppat.1006720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699845/
https://www.ncbi.nlm.nih.gov/pubmed/29125880
http://dx.doi.org/10.1371/journal.ppat.1006720

Ejemplares similares