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E3 ubiquitin ligase Bre1 couples sister chromatid cohesion establishment to DNA replication in Saccharomyces cerevisiae

Bre1, a conserved E3 ubiquitin ligase in Saccharomyces cerevisiae, together with its interacting partner Lge1, are responsible for histone H2B monoubiquitination, which regulates transcription, DNA replication, and DNA damage response and repair, ensuring the structural integrity of the genome. Dele...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Yeung, Clarence Hue Lok, Wu, Liwen, Yuen, Karen Wing Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699866/
https://www.ncbi.nlm.nih.gov/pubmed/29058668
http://dx.doi.org/10.7554/eLife.28231

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