Cargando…

Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?

Early oocytes of nearly all animal species contain a transient organelle assemblage termed the Balbiani body. Structure and composition of this assemblage may vary even between closely related species. Despite this variability, the Balbiani body always comprises of numerous tightly clustered mitocho...

Descripción completa

Detalles Bibliográficos
Autores principales: Bilinski, Szczepan M., Kloc, Malgorzata, Tworzydlo, Waclaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699987/
https://www.ncbi.nlm.nih.gov/pubmed/28755153
http://dx.doi.org/10.1007/s10815-017-1006-3
_version_ 1783281044443627520
author Bilinski, Szczepan M.
Kloc, Malgorzata
Tworzydlo, Waclaw
author_facet Bilinski, Szczepan M.
Kloc, Malgorzata
Tworzydlo, Waclaw
author_sort Bilinski, Szczepan M.
collection PubMed
description Early oocytes of nearly all animal species contain a transient organelle assemblage termed the Balbiani body. Structure and composition of this assemblage may vary even between closely related species. Despite this variability, the Balbiani body always comprises of numerous tightly clustered mitochondria and accumulations of nuage material. It has been suggested that the Balbiani body is an evolutionarily ancestral structure, which plays a role in various processes such as the localization of organelles and macromolecules to the germ plasm, lipidogenesis, as well as the selection/elimination of dysfunctional mitochondria from female germline cells. We suggest that the selection/elimination of mitochondria is a primary and evolutionarily ancestral function of Balbiani body, and that the other functions are secondary, evolutionarily derived additions. We propose a simple model explaining the role of the Balbiani body in the selection of mitochondria, i.e., in the mitochondrial DNA (mtDNA) bottleneck phenomenon.
format Online
Article
Text
id pubmed-5699987
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-56999872017-12-04 Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? Bilinski, Szczepan M. Kloc, Malgorzata Tworzydlo, Waclaw J Assist Reprod Genet Review Early oocytes of nearly all animal species contain a transient organelle assemblage termed the Balbiani body. Structure and composition of this assemblage may vary even between closely related species. Despite this variability, the Balbiani body always comprises of numerous tightly clustered mitochondria and accumulations of nuage material. It has been suggested that the Balbiani body is an evolutionarily ancestral structure, which plays a role in various processes such as the localization of organelles and macromolecules to the germ plasm, lipidogenesis, as well as the selection/elimination of dysfunctional mitochondria from female germline cells. We suggest that the selection/elimination of mitochondria is a primary and evolutionarily ancestral function of Balbiani body, and that the other functions are secondary, evolutionarily derived additions. We propose a simple model explaining the role of the Balbiani body in the selection of mitochondria, i.e., in the mitochondrial DNA (mtDNA) bottleneck phenomenon. Springer US 2017-07-28 2017-11 /pmc/articles/PMC5699987/ /pubmed/28755153 http://dx.doi.org/10.1007/s10815-017-1006-3 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Bilinski, Szczepan M.
Kloc, Malgorzata
Tworzydlo, Waclaw
Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?
title Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?
title_full Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?
title_fullStr Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?
title_full_unstemmed Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?
title_short Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?
title_sort selection of mitochondria in female germline cells: is balbiani body implicated in this process?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699987/
https://www.ncbi.nlm.nih.gov/pubmed/28755153
http://dx.doi.org/10.1007/s10815-017-1006-3
work_keys_str_mv AT bilinskiszczepanm selectionofmitochondriainfemalegermlinecellsisbalbianibodyimplicatedinthisprocess
AT klocmalgorzata selectionofmitochondriainfemalegermlinecellsisbalbianibodyimplicatedinthisprocess
AT tworzydlowaclaw selectionofmitochondriainfemalegermlinecellsisbalbianibodyimplicatedinthisprocess