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Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?
Early oocytes of nearly all animal species contain a transient organelle assemblage termed the Balbiani body. Structure and composition of this assemblage may vary even between closely related species. Despite this variability, the Balbiani body always comprises of numerous tightly clustered mitocho...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699987/ https://www.ncbi.nlm.nih.gov/pubmed/28755153 http://dx.doi.org/10.1007/s10815-017-1006-3 |
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author | Bilinski, Szczepan M. Kloc, Malgorzata Tworzydlo, Waclaw |
author_facet | Bilinski, Szczepan M. Kloc, Malgorzata Tworzydlo, Waclaw |
author_sort | Bilinski, Szczepan M. |
collection | PubMed |
description | Early oocytes of nearly all animal species contain a transient organelle assemblage termed the Balbiani body. Structure and composition of this assemblage may vary even between closely related species. Despite this variability, the Balbiani body always comprises of numerous tightly clustered mitochondria and accumulations of nuage material. It has been suggested that the Balbiani body is an evolutionarily ancestral structure, which plays a role in various processes such as the localization of organelles and macromolecules to the germ plasm, lipidogenesis, as well as the selection/elimination of dysfunctional mitochondria from female germline cells. We suggest that the selection/elimination of mitochondria is a primary and evolutionarily ancestral function of Balbiani body, and that the other functions are secondary, evolutionarily derived additions. We propose a simple model explaining the role of the Balbiani body in the selection of mitochondria, i.e., in the mitochondrial DNA (mtDNA) bottleneck phenomenon. |
format | Online Article Text |
id | pubmed-5699987 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-56999872017-12-04 Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? Bilinski, Szczepan M. Kloc, Malgorzata Tworzydlo, Waclaw J Assist Reprod Genet Review Early oocytes of nearly all animal species contain a transient organelle assemblage termed the Balbiani body. Structure and composition of this assemblage may vary even between closely related species. Despite this variability, the Balbiani body always comprises of numerous tightly clustered mitochondria and accumulations of nuage material. It has been suggested that the Balbiani body is an evolutionarily ancestral structure, which plays a role in various processes such as the localization of organelles and macromolecules to the germ plasm, lipidogenesis, as well as the selection/elimination of dysfunctional mitochondria from female germline cells. We suggest that the selection/elimination of mitochondria is a primary and evolutionarily ancestral function of Balbiani body, and that the other functions are secondary, evolutionarily derived additions. We propose a simple model explaining the role of the Balbiani body in the selection of mitochondria, i.e., in the mitochondrial DNA (mtDNA) bottleneck phenomenon. Springer US 2017-07-28 2017-11 /pmc/articles/PMC5699987/ /pubmed/28755153 http://dx.doi.org/10.1007/s10815-017-1006-3 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Review Bilinski, Szczepan M. Kloc, Malgorzata Tworzydlo, Waclaw Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? |
title | Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? |
title_full | Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? |
title_fullStr | Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? |
title_full_unstemmed | Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? |
title_short | Selection of mitochondria in female germline cells: is Balbiani body implicated in this process? |
title_sort | selection of mitochondria in female germline cells: is balbiani body implicated in this process? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699987/ https://www.ncbi.nlm.nih.gov/pubmed/28755153 http://dx.doi.org/10.1007/s10815-017-1006-3 |
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