Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis

Checkpoint kinase 1 (CHK1) is critical for intrinsic cell cycle control and coordination of cell cycle progression in response to DNA damage. Despite its essential function, CHK1 has been identified as a target to kill cancer cells and studies using Chk1 haploinsufficient mice initially suggested a...

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Detalles Bibliográficos
Autores principales: Schuler, Fabian, Weiss, Johannes G., Lindner, Silke E., Lohmüller, Michael, Herzog, Sebastian, Spiegl, Simon F., Menke, Philipp, Geley, Stephan, Labi, Verena, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700047/
https://www.ncbi.nlm.nih.gov/pubmed/29167438
http://dx.doi.org/10.1038/s41467-017-01850-4

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