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Telomerase activity is required for the telomere G-overhang structure in Trypanosoma brucei

Trypanosoma brucei causes fatal human African trypanosomiasis and evades the host immune response by regularly switching its major surface antigen, VSG, which is expressed exclusively from subtelomeric loci. Telomere length and telomere proteins play important roles in regulating VSG silencing and s...

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Detalles Bibliográficos
Autores principales:	Sandhu, Ranjodh, Li, Bibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700094/ https://www.ncbi.nlm.nih.gov/pubmed/29167542 http://dx.doi.org/10.1038/s41598-017-16182-y

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