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Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production
Metformin is a widely used and well-tolerated anti-diabetic drug that can reduce cancer risk and improve the prognosis of certain malignancies. However, the mechanism underlying its anti-cancer effect is still unclear. We studied the anti-cancer activity of metformin on colorectal cancer (CRC) by us...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700100/ https://www.ncbi.nlm.nih.gov/pubmed/29167573 http://dx.doi.org/10.1038/s41598-017-16149-z |