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Functional germline variants as potential co-oncogenes
Germline variants that affect the expression or function of proteins contribute to phenotypic variation in humans and likely determine individual characteristics and susceptibility to diseases including cancer. A number of high penetrance germline variants that increase cancer risk have been identif...
Autores principales: | Agarwal, Divyansh, Nowak, Christoph, Zhang, Nancy R., Pusztai, Lajos, Hatzis, Christos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700137/ https://www.ncbi.nlm.nih.gov/pubmed/29177190 http://dx.doi.org/10.1038/s41523-017-0051-5 |
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