Stochastic fluctuations can reveal the feedback signs of gene regulatory networks at the single-molecule level

Understanding the relationship between spontaneous stochastic fluctuations and the topology of the underlying gene regulatory network is of fundamental importance for the study of single-cell stochastic gene expression. Here by solving the analytical steady-state distribution of the protein copy num...

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Detalles Bibliográficos
Autores principales: Jia, Chen, Xie, Peng, Chen, Min, Zhang, Michael Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700158/
https://www.ncbi.nlm.nih.gov/pubmed/29167445
http://dx.doi.org/10.1038/s41598-017-15464-9

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