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CRISPR-Cas-Mediated Gene Silencing Reveals RacR To Be a Negative Regulator of YdaS and YdaT Toxins in Escherichia coli K-12

Bacterial genomes are rich in horizontally acquired prophages. racR is an essential gene located in the rac prophage that is resident in many Escherichia coli genomes. Employing a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas-based gene silencing approach, we show that RacR i...

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Detalles Bibliográficos
Autores principales:	Bindal, Gargi, Krishnamurthi, Revathy, Seshasayee, Aswin Sai Narain, Rath, Devashish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700377/ https://www.ncbi.nlm.nih.gov/pubmed/29205229 http://dx.doi.org/10.1128/mSphere.00483-17

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