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Thrombin-Induced Calpain Activation Promotes Protease-Activated Receptor 1 Internalization

The serine protease thrombin activates Protease-Activated Receptors (PARs), a family of G-protein-coupled receptors (GPCRs) activated by the proteolytic cleavage of their extracellular N-terminal domain. Four members of this family have been identified: PAR1–4. The activation of Protease-Activated R...

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Detalles Bibliográficos
Autores principales:	Alvarez-Arce, Alejandro, Lee-Rivera, Irene, López, Edith, Hernández-Cruz, Arturo, López-Colomé, Ana María
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700505/ https://www.ncbi.nlm.nih.gov/pubmed/29250115 http://dx.doi.org/10.1155/2017/1908310

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